KRT20 anticorps

N° du produit ABIN114613

Cet anticorps Souris Monoclonal détecte spécifiquement KRT20 dans IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour KRT20 anticorps (ABIN114613)

Antigène: KRT20 (Keratin 20 (KRT20))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT20 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: Ks20-8

Détail du produit anti-KRT20 anticorps

Specificité: This antibody reacts with cytokeratin polypeptide of 46 kDa in immunoblott analyses.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogène: Cytokeratins isolated from human micro dissected villi of human duodenal mucosa.

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: Use a dilution of 1/25-1/50 in an ABC method(30 minutes at room temperature). Formalin fixed paraffin embedded tissue sectionsrequire high temperature antigen unmasking with 10 mM Citrate buffer, pH 6.0 prior toimmunostaining. Positive Control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur KRT20

Antigène: KRT20 (Keratin 20 (KRT20))

Autre désignation: Cytokeratin 20

Sujet: Cytokeratin 20 is a 46 kDa intermediate filament protein whose expression is restricted primarily to gastric and intestinal epithelium, urothelium, and Merkel cells. This antibody is highly specific to cytokeratin 20 and shows no cross-reactivity with other IFPs. Cytokeratin 20 is a unique type I keratin that is expressed in adenocarcinomas of the colon stomach, pancreas and bile system. It is also expressed in mucinous ovarian tumors, transitional cell carcinomas of the urinary tract, and Merkel cell carcinomas. This antibody is essentially non-reactive in squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas. This antibody is often used in conjunction with CK7 and other antibodies to distinguishing colon carcinomas (CK20+), from ovarian, pulmonary, and breast carcinomas.Synonyms: CK20, Cytokeratin 20, K20, KRT20, Keratin type I cytoskeletal 20, Keratin-20, Protein IT

ID gène: 54474

NCBI Accession: NP_061883

UniProt: P35900